Intrarenal Transport and Vasoactive Substances in Hypertension

Intrarenal transport and vasoactive substances in hypertension.

Blood pressure is influenced by several vasoactive factors that also regulate nephron transport. An imbalance in regulation of salt reabsorption by the nephron contributes to hypertension. In the spontaneously hypertensive rat (SHR), the responses to dopamine and angiotensin II in the proximal nephron are diminished and enhanced, respectively. This partially explains why the proximal tubule of ...

The role of intrarenal vasoactive substances in the pathogenesis of essential hypertension.

Prednison provokes serum and vasoactive substances in a mice model of immune thrombocytopenia

Objective(s): The main objective of this study was to investigate the variations of β-endorphin (β-EP), vasoactive intestinal peptide (VIP), serotonin (5-HT) and norepinephrine (NE) of immune thrombocytopenia (ITP) mice as well as the regulatory mechanism of prednison. Materials and Methods: Sixty BALB/c mice were randomly divided into control group, model group and prednison intervention grou...

The interaction of vasoactive substances during exercise modulates platelet aggregation in hypertension and coronary artery disease

BACKGROUND Acute vigorous exercise, associated with increased release of plasma catecholamines, transiently increases the risk of primary cardiac arrest. We tested the effect of acute submaximal exercise on vasoactive substances and their combined result on platelet function. METHODS Healthy volunteers, hypertensive patients and patients with coronary artery disease (CAD) performed a modified...

Vasoactive Substances and Inflammatory Factors in Progression of Liver Cirrhosis with Portal Hypertension